Legacy

The discovery of insulin in 1921 was a great medical advancement in diabetes care. Approximately sixty years later, another great milestone paralleled the first: the development of recombinant human insulin. And with the discovery of insulin, Eli Lilly and Company played a significant role by perfecting the large-scale manufacture of human insulin.

In 1982, the U.S. Food and Drug Administration approved Humulin, Lilly's human insulin, for marketing. It was the first commercially available, genetically engineered human insulin on the market and the first pharmaceutical product derived from recombinant DNA technology -another first in diabetes care for Lilly.

Today, in most parts of the world, 95 percent of insulin users take some form of human insulin.


References:

Standards of Medical Care in Diabetes2015. DIABETES Care 2015;3 (Suppl. 1)
Harrison’s Principles of Internal Medicine, edition 18, chapters 35, 94, 218, 21, 344
ISPAD Clinical Practice Consensus Guidelines 2014
Uptodate: Overview of medical care in adults with diabetes mellitus Author David K McCulloch, MD, Mar 18-2015
Uptodate: Glycemic control and vascular complication in type 2 diabetes mellitus, Author David K McCulloch, MD, Jun 2015

 

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